PowerPlex(R) 18D Panel, Bin, and Stutter File Revision History

Original Release (v1.0):  02/28/2011
PowerPlex_18D_Panels_IDX_v1.0
PowerPlex_18D_Bins_IDX_v1.0
PowerPlex_18D_Stutter_IDX_v1.0

Version 1.1 Release:  06/15/2011
Corrected virtual bin base pair size for CSF1PO allele 10.3
Underscore removed from Penta E and Penta D
PowerPlex_18D_Panels_IDX_v1.1
PowerPlex_18D_Bins_IDX_v1.1
PowerPlex_18D_Stutter_IDX_v1.1

Version 1.2 Release:  08/01/2011
Updated virtual bin base pair size for CSF1PO allele 10.3
Changed bin width on all bins within 1 base pair of another to 0.5bp below and 0.4bp above bin center.
Sizing of virtual bins based on arithmetic estimation using nearest real allele below and above virtual allele bin.
PowerPlex_18D_Panels_IDX_v1.2
PowerPlex_18D_Bins_IDX_v1.2
PowerPlex_18D_Stutter_IDX_v1.2

Version 1.3 Release:  02/2015
Changed minimum stutter distance for Penta E and Penta D from 3.75 to 4.25
PowerPlex_18D_Panels_IDX_v1.3
PowerPlex_18D_Bins_IDX_v1.3
PowerPlex_18D_Stutter_IDX_v1.3 


Version 2.0 Release:  05/2015
Allele sizing and panel ranges based on mean sizing values observed between 31XX and 35XX instrument platforms using POP-4(TM) Polymer with WEN ILS 500 size standard.

Additional virtual alleles added for following loci to match virtual alleles present in bins for loci shared between PowerPlex 18D and Fusion 6C Systems:

D3S1358: 14.3, 15.1, 15.3, 16.2, 17.2, 18.1, 18.2, 18.3
TH01: 5.3, 6.1, 6.3, 7.1, 7.3, 9.1
D21S11: 23.3, 30.1, 31.3, 32.3, 33.3, 34.3
D18S51: 12.3, 13.1, 15.3, 16.3, 17.3, 21.1, 23.2, 24.2
Penta E: 11.4, 14.2, 15.2, 17.4
D5S818: 6, 10.1, 12.1, 12.3
D13S317: 7.1, 12.3, 13.3
D7S820: 7.1, 8.2, 9.2, 11.2, 12.3, 14.1, 15
D16S539: 7, 8.3, 10.3, 12.2, 16
CSF1PO: 8.1, 10.1, 11.1, 11.3, 12.3, 13.3
Penta D: 6.4, 7.4, 8.2, 9.2, 9.4, 11.1, 11.2, 12.1, 13.4, 14.4, 18
vWA: 16.1, 18.2, 18.3
D8S1179: 6, 12.3, 13.2, 13.3, 14.1, 15.1, 15.3
TPOX: 7.1, 7.3, 10.1, 10.3
FGA: 12.2, 16.2, 19.1, 21.1, 26.3, 27.3, 28.3, 29.1, 32, 51.2
D19S433: 6, 8.2, 11.1, 13.1, 14.1, 14.3, 16.1, 18.1
D2S1338: 22.2, 29

PowerPlex_18D_Panels_IDX_v2.0
PowerPlex_18D_Bins_IDX_v2.0
PowerPlex_18D_Stutter_IDX_v2.0